Trainees

Select the lab you are interested in to find out about current PDF and graduate student research projects.
Campanucci Lab

Zeinab Momeni (PhD candidate)
In my research, I am investigating the hyperglycemia-induced cellular and biochemical changes in central neurons from the hippocampus. To do that, I am using electrophysiological techniques, as well behavioral testing to determine the relationship between diabetes and AD-like cognitive deficits, and learning and memory impairments.

 

Caruncho Lab
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Sukina Albuhussain (Msc Candidate)

Josh Allen (Msc Candidate)

Raquel

Dr. Raquel Romay-Tallon (Post-Doctoral Fellow)

Cayabyab Lab
adelaide

Adelaid Amah (MSc Candidate)

I currently work on repurposing metformin, an anti-diabetic drug for use in the prevention and therapeutic management of Parkinson's disease in our novel chronic injection animal model for the disorder. I look at the relationship between neurodegeneration, adenosine and insulin-related signalling mechanisms in the ageing brain using behavioural testing, electrophysiology, immunohistochemistry and biochemistry techniques. 

Le Gui

 Dr. Le Gui (Postdoctoral Research Associate)

My project is to investigate the role of the HERG (Human Ether-à-go-go-Related Gene) channel in human breast cancer cell growth. Currently, I am using patch clamp electrophysiology to correlate HERG expression in different human breast cancer cells with their proliferation, in the hopes that these findings will ultimately lead to the development of therapeutic agents to prevent, detect, and treat breast cancers and possibly other types of cancers.

Elisabet Jakova

Elisabet Jakova (PhD candidate)

I am currently studying the role of adenosine signalling and alpha-synuclein misfolding based on a chronic injection rat model that mimics Parkinsonian syndrome.  I am also testing several novel dimer drugs that bind to alpha-synuclein and prevent its misfolding in vitro, and am currently characterizing the possible neuroprotective efficacy of these compounds in our novel animal model of Parkinson’s disease.

Jay

Hye Ji (Jay) Kim (MSc candidate)

I am aiming to delineate the functional interaction between the cheomokine receptor 2 (CXCR2) and the adenosine 1 receptor (A1R), and how their intracellular signalling systems cause microglial activation in neurodegenerative disorders such as ischemic stroke and frontal lobe epilepsy. I also hope to shed light on how adenosine signalling is involved in the morphological shifts between M1 (proinflammatory) and M2 (anti-inflammatory) microglia phenotypes during neurodegenerative events.

Jasleen

Jasleen Saini (Summer/Honors Student)

I am investigating the role of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in synaptic plasticity and neurodegeneration using a variety of techniques, including electrophysiology, imaging, biochemistry, behavioural tests and intranasal drug application.  My work aims to increase our understanding of HCN channel contribution to brain function, especially in animal models that mimic the aging brain with elevated adenosine. 

JS Jocelyn Stockwell (PhD Candidate)

I am a PhD student studying the role of adenosine signalling and immune cell activation in neurodegenerative disorders including stroke, Parkinson’s disease, and epilepsy. I am currently working on developing a novel animal model for Parkinson’s disease that may give us more insight into the development and early stages of the disease.

Ivan

Xin Qin (MSc Candidate)

I am currently working on the relationship between Adenosine A1 and A2A receptors in the hippocampus and AMPA receptors’ role in several neurological diseases, such as stroke and Parkinson's disease

Vincent

Dr. Yuncheng (Vincent) Lv (Postdoctoral Fellow)

My project investigates whether long-term activation of adenosine receptor A1 receptors in the brain subsequently leads to upregulation of neuron sortilin, believed to play a crucial role in lipid transport in neurons. I will determine whether A1R stimulation leads to intracellular lipid accumulation by increasing sortilin expression, which contributes to increased lipidation of alpha-synuclein and development of Parkinson’s disease.

Zaki

Michael Zaki (MSc Candidate)

I am an MSc student investigating the role of A1 and A2A receptor and AMPA receptor signalling in neurodegenerative disease, especially stroke.  I am also studying the efficacy of clinically approved drug perampanel in an animal stroke model.

Fisher Lab
 
Howland Lab
Kalynchuk Lab
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Kyle Brymer (PhD candidate)
My research examines the effects of repeated corticosterone (CORT) injections on rodent performance of tasks of executive functioning. We employ a variety of behavioral paradigms, including the forced swim test (FST), object memory tasks, and prepulse inhibition (PPI). Work in the future will examine the influence of NMDA receptor antagonists (ex. Ketamine) and immune blockers (ex. Etanercept) on CORT-treated rats' performance on the above mentioned behavioral paradigms.
Brian Kulyk (MSc candidate)
mm Milann Mitchell (MSc candidate)
Nikita Nogovitsyn (MSc candidate)
Mousseau Lab
KK Kaeli Knudsen (MSc candidate)
old jen Dr. Jennifer Nyarko (Post-Doctoral Fellow)
Lisa Lisa Poon (Msc candidate)
maa Dr. Maa Quartey (Post-Doctoral Fellow)
 
Mulligan Lab
Nazarali Lab
Natasha Breward (MSc candidate)
Ran Bi (PhD candidate)
My study: Homeobox (Hox) genes are homeodomain-containing transcription factors that specify cell identity in early development and are also involved in several human diseases. Hoxa2 is the first Hox genes to be activated in embryo development and are critical for hindbrain ear and palate development. My study is focused on how epigenetic marks such as histone methylation and siRNA can regulate the expression of Hoxa2.
kf Kendra Furber (Post-Doctoral fellow)
Paul Pown Raj Iyyanar (PhD candidate)
Paul is a PhD student under the supervision of Dr. Nazarali. He joined Dr. Nazarali's lab as a graduate student in September 2011. After completing Masters in Biotechnology, Paul worked for two years as a Junior Research Fellow in protein separation and mass spectrometry working on biomarkers for primary open angle glaucoma. His Masters thesis was on genetic analysis using mitochondrial and Y- chromosome markers to study the ancestry of on an ethnic population in Tamil Nadu, India. His PhD research focuses are investigating the molecular mechanisms governing proper palate development and in the etiology of cleft palate. 
glai Glaiza Tan (PhD candidate)
Merlin Thangaraj (PhD candidate)
Merlin joined Dr. Nazarali's lab in September 2011 to pursue her PhD. Her Masters dissertation was on anti-hepatotoxic effect of Citrus Limon on hepatotoxicity. She completed the National Eligibility Test conducted by CSIR –UGC for Lectureship. Later she worked as a research scholar in the field of Immunology and Molecular biology. At present she is investigating the role of Sirtuin2 in myelination and the aging brain.
Paterson Lab
sc Sally Caine (Post-Doctoral Fellow)
Andrew Crawford (Post-Doctoral Fellow)
Angie Li (MSc candidate)
I come from Harbin, China. Currently, I am a 2nd year Master Student in Dr. Paterson's Lab. My research interest is to study the effect of post-stroke Protein-Energy Malnutrition (PEM) on stroke outcome in terms of functional recovery and changes in neuroplastic markers. The brain ischemia model we are using is the photothrombotic stroke model. I use the horizontal ladder test to assess functional outcome as well as immuno-histochemistry to study neurological mechanisms.
Larisa Matwee (MSc candidate)
Taghibiglou Lab
Omran Entisar (Post-Doctoral Fellow)
haj Hajar Miranzadeh (MSc candidate)
Hannah Hanan Mohammad (MSc sandidate

Nathan Pham (PhD candidate)

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Sathiya Sekar (Post-Doctoral Fellow)

Anna Siqingaowa (MSc Candidate)