Dr. Mohan Babu Neuroscience Cluster Associate Member
Dr. Babu is an Associate Professor in the Department of Biochemistry at the University of Regina. He is an internationally recognized leader in network biology, and a pioneer for mapping epistatic relationships and membrane-associated protein complexes in prokaryotes and eukaryotes. His research excellence has been acknowledged with a CIHR-IG Maud Menten new investigator award. He is an advisory board member of the international mitochondrial (mt) human proteome initiative and a team leader of the mitoNET Canada. Building on years of groundwork using large-scale proteomics and quantitative genetics, his research work aims to address how mt protein dysfunction contributes to the pathogenesis of neurodegenerative disorders (e.g. Alzheimer's, Parkinson's, ALS), and how these disease associated mt proteins organize and function in cellular pathways and macromolecular assemblies in human neurons. By focusing on these gaps, he aims to uncover causal mechanisms and mt protein-specific pathway targets to treat the underlying mt disorders.